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Naturacare
naturacare.jp › home › blog › nattokinase dose per day: evidence-based guide
Nattokinase Dose Per Day: Evidence-Based Guide – Naturacare
March 25, 2026 - The largest clinical study (1,062 ... a randomized trial · FU (Fibrinolytic Units) measure enzyme activity, not weight — two "100 mg" nattokinase products can have very different potencies if FU is not specified...
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Bio Absorb Nutraceuticals
bioabsorbnutraceuticals.com › home › nattokinase guide › how much nattokinase per day?
How much nattokinase per day? – Bio Absorb Nutraceuticals
Nattokinase Enzyme - Non-GMO nattokinase enzyme (natto extract) for cardiovascular health support. 100mg per serving, 2000 FU activity, 60 or 180 veggie capsules.
Price: $28.18
Discussions

Nattokinase - which brand and does it worth it
Rules of r/supplements Do Not Suggest Prescription Drugs Posts & Comments Reported as: Do Not Suggest Prescription Drugs Prescription drugs are not Supplements; do not recommend prescription medication. Sensible/Suggest talking to DR. can be allowable etc 2. Dangerous Grey Area Substance Posts & Comments Reported as: Dangerous Grey Area Substance Potentially dangerous grey area substances can not be recommended. 3. Be Polite Posts & Comments Reported as: Rude/Personal Attacks You shouldn't ever be personally attacking another user in this subreddit. 4. No Advertisements Posts & Comments Reported as: Advertisement. No selling / buying / trading posts No advertisements. No selling/trading posts between users.” I am a bot, and this action was performed automatically. Please contact the moderators of this subreddit if you have any questions or concerns. More on reddit.com
🌐 r/Supplements
72
19
October 10, 2025
Sollte man das Natto-Supplement 10.800 FU alles auf ...
I know that the study said the participants took 10,800 FU of the supplement, but was it all at once or can you space it out? I know most ppl take… More on reddit.com
🌐 r/Supplements
To those of you taking nattokinase, what dosage are you taking per day?
I would also like to know. I would also like to see some science that backs up what dose might actually work. Is 2000 FU enough? Is it better to take serrapeptase with nattokinase at the same time? How long should you be taking it? So many questions...we need some science based answers! More on reddit.com
🌐 r/covidlonghaulers
93
24
February 4, 2023
Management of atherosclerosis with 10,800 FU of Nattokinase
Wow, that's interesting. Both hypertension and atherosclerosis are really dangerous, and kill so many people. There's also no currently known medicine that reverses atherosclerosis. So if nattokinase not only treats hypertension, but also reverses atherosclerosis, wouldn't that make it absolutely revolutionary? Why isn't it popular now, since the study is from 2022? I wonder if there's a catch or something. More on reddit.com
🌐 r/Biohackers
37
42
August 1, 2025
People also ask

What is the difference between FU and mg in nattokinase?
FU (Fibrinolytic Units) measure nattokinase's enzyme activity — how effectively it dissolves fibrin clots. Milligrams measure weight. The approximate conversion is 2,000 FU per 100 mg, but this varies by manufacturer. FU is the clinically meaningful metric. A product that only lists milligrams without specifying FU does not provide enough information to assess its potency. Look for products with FU clearly stated on the label.
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naturacare.jp
naturacare.jp › home › blog › nattokinase dose per day: evidence-based guide
Nattokinase Dose Per Day: Evidence-Based Guide – Naturacare
How many FU of nattokinase per day?
Many studies have used about 2,000 FU a day, and the largest long-term study used 10,800 FU. There's no official recommended intake, so pick the studied amount that fits your goal and check the FU per serving on your label.
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microingredients.com
microingredients.com › blogs › microingredients-updated › nattokinase-dosage
Nattokinase Dosage: How Many FU Per Day – Micro Ingredients
Can I take 10,000 FU of nattokinase daily?
The largest clinical study used 10,800 FU daily for 12 months in 1,062 participants without reported adverse effects. However, this was a physician-supervised observational study, not a self-directed protocol. If you are considering doses at this level, consult your healthcare provider — especially if you take any medications that affect blood clotting.
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naturacare.jp
naturacare.jp › home › blog › nattokinase dose per day: evidence-based guide
Nattokinase Dose Per Day: Evidence-Based Guide – Naturacare
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BlueRipple Health
blueripple.com › natto › natto-dosing
Nattokinase Dosing and Administration - BlueRipple Health
December 11, 2025 - Common formulations range from 1,000 FU to 4,000 FU per capsule, with some products claiming higher activities. A 2,000 FU dose typically corresponds to roughly 100 mg of nattokinase, though this ratio depends on enzyme purity and manufacturing ...
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Toku
tokuhealth.com › home › blog
Nattokinase Dosage: How Much Should You Take? – Toku
3 weeks ago - The clinically studied dosage of nattokinase is 10,800 fibrinolytic units (FU), significantly higher than the 2,000 FU found in most commercial supplements. Think of it this way: if a clinical study tested a medication at 100 mg and found it effective, you wouldn't expect a 20 mg ...
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Nattokinase
nattokinase.info › news › milligrams-mg-vs-fibrin-units-fu
Milligrams (mg) vs. Fibrin Units (FU) - Nattokinase.Info
This article explains the difference between the measurements of milligrams and fibrin units.
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Examine
examine.com › home › supplements › nattokinase
Nattokinase benefits, dosage, and side effects
March 16, 2026 - People living in China have taken 540 mg (10,800 FU) of nattokinase daily for a year,[6] and adults living in the United States have taken 552 mg of nattokinase daily for four weeks[2] without any reported adverse effects.
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NIH
dsld.od.nih.gov › label › 246790
Nattokinase 800 mg 4000 FU (Label)
NIH's Dietary Supplement Label Database (DSLD) is a searchable database of current and historical label information from products marketed in the U.S.
Find elsewhere
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Micro Ingredients
microingredients.com › blogs › microingredients-updated › nattokinase-dosage
Nattokinase Dosage: How Many FU Per Day – Micro Ingredients
3 weeks ago - In the 12-month study no noticeable adverse effects were recorded at 10,800 FU a day, and a review of the research describes healthy volunteers tolerating 10 mg per kilogram of body weight daily for four weeks.
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Nattokinase Hub
nattokinasehub.com › home › dosage and safety › nattokinase dosage guide: fu units, effective amounts, and timing
Nattokinase Dosage: FU Units, Amounts, and Timing
July 10, 2026 - When you pick up a nattokinase supplement, you may see the dose listed as 100 mg, 2,000 FU, or both. The milligram figure tells you how much powder is in the capsule. The FU figure — Fibrinolytic Unit — tells you how enzymatically active ...
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Double Wood Supplements
doublewoodsupplements.com › home › nattokinase supplement
Nattokinase Supplement (4000 FU) | Double Wood Supplements
Nattokinase Supplement - Nattokinase is a serine protease enzyme isolated from natto, a traditional Japanese fermented soybean food, first identified by Dr. Hiroyuki Sumi in 1980. Nattokinase is an enzyme studied for its role in supporting healthy circulation and cardiovascular wellness.* FU, fibrin units, measures enzyme activity.This product provides 4,000 FU per serving, verified by third-party testing. Double Wood's formula delivers 4,000 FU (fibrin units) per 2-capsule serving, within the 2,000 to 10,800 FU range studied in published human research, with enzymatic activity verified every batch by an ISO/IEC 17025
(4.8)
Price: $19.95
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Dr. Berg
drberg.com › home › nutrition › health benefits of nattokinase
Health Nattokinase Benefits – Heart Support | Dr. Berg
Recommended dosages of nattokinase ... from 50 to 200 milligrams daily, which should provide around 2000 FU, a measure of the enzymatic activity of nattokinase. However, a recent study published in Frontiers in Cardiovascular Medicine demonstrated that a significantly higher dose of oral nattokinase at 10,800 FU per day not only appears to be safe but may also be more effective in supporting markers of cardiovascular wellness....
Published: April 9, 2025
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Remedysnutrition
remedysnutrition.com › home › heart health & cardiovascular support › nattokinase dosage: what fu means and why 2,000 is the number
Nattokinase Dosage: What FU Means and Why 2,000
1 month ago - The dose with the clearest trial behind it is 2000 FU, used in a double-blind crossover study in 12 healthy men. FU stands for fibrin units and measures enzyme activity, not weight, so 2000 FU is about 100 mg.
Address: 99696 Overseas Hwy, Suite 5, 33037, Key Largo
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PubMed Central
pmc.ncbi.nlm.nih.gov › articles › PMC9441630
Effective management of atherosclerosis progress and hyperlipidemia with nattokinase: A clinical study with 1,062 participants - PMC
Nattokinase used throughout the study was administered orally as a nattokinase tablet approved by the China National Medical Products Administration (NMPA) and manufactured by Sungen Bioscience Co, Ltd, Shantou, China. Each tablet contained 3,600 FU. The oral dosage used was 10,800 FU daily.
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Toku
tokuhealth.com › home › nattokinase 10,800 fu supplement | soy-free
Nattokinase 10,800 FU Supplement, Soy-Free | Toku Flow
Nattokinase 10,800 FU Supplement | Soy-Free - Most Powerful Cardiovascular ProtocolToku Flow delivers 10,800 FU of clinical-grade nattokinase per daily sachet, paired with 180 mcg of Vitamin K2 (MK-7) and oat beta-glucan for comprehensive cardiovascular support. Sourced from chickpea fermentation (soy-free), third-party tested, no fillers.
(4.8)
Price: $179.97
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Amazon
amazon.com › Toku-Nattokinase-Circulation-Plant-Based-Single-Serve › dp › B0FW6CK7MT
Amazon.com: Toku Nattokinase 10,800 FU Heart Supplement Powder | Unflavored 30 Servings | Soy Free Natto Enzyme + Vitamin K2 & Beta Glucan | Supports Circulation, Cholesterol, Blood Pressure & Cardiovascular Health : Health & Household
BulkSupplements BulkSupplements.com ... 4000 FU - Sourced from Natto Extract, 100mg per Serving, 50g (1.8 oz) (Pack of 1) ... Matcharl Matcharl Japanese Natto Powder, Freeze-Dried, 50g/1.76oz | Freeze-Dried Natto, Nattokinase & Vitamin K2, Non-GMO, Vegan, Made in Japan ... NOW Foods NOW Supplements, Nattokinase 100 mg (from Non-GMO ...
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Drugs.com
drugs.com › home › natural products (pro) › nattokinase
Nattokinase Uses, Benefits & Dosage
January 22, 2026 - Nattokinase 100 mg/day (equivalent to 2,000 fibrinolytic units [FU]), typically for a duration of 8 weeks, has been used in some studies evaluating thrombolytic/fibrinolytic and blood pressure effects.
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ScienceDirect
sciencedirect.com › science › article › pii › S0141813024025844
Nattokinase attenuates endothelial inflammation through the activation of SRF and THBS1 - ScienceDirect
April 27, 2024 - Furthermore, NK was shown to protect ... study indicated that a high intake of natto at a dose of 10,800 FU/day for 12 months is related to a lower risk of atherosclerosis progression to ASCVD [20]. Dietary natto supplements ...
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Dr Brad Stanfield
drstanfield.com › blogs › articles › nattokinase-benefits-forms-dosing-and-side-effects
Nattokinase: Benefits, Forms, Dosing, and Side Effects – Dr Brad Stanfield
Daily doses between 2,000 FU and 4,000 FU (and 100 mg to 650 mg) have been used in most clinical studies [1]. Due to a lack of definitive clinical evidence, it is not clear what dose is optimal for any specific indication.
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Protocol for Life
protocolforlife.com › home › nattokinase
Nattokinase 100 mg, 2,000 FU - Protocol for Life Balance
May 19, 2025 - Nattokinase is an enzyme isolated from natto, a traditional Japanese fermented soy food that has been consumed for thousands of years for its numerous health promoting properties.* More recently, both clinical and non-clinical studies have demonstrated that nattokinase can promote heart and circulatory health by helping to maintain normal blood fluidity.* Each serving of Protocol For Life Balance® Non-GMO Nattokinase has 2,000 FUs (Fibrinolytic Units) for the maintenance of proper blood flow.*