We observed that mean serum Vitamin B12 (198.07 ± 88.98 pg/ml in cases vs. 343.07 ± 143.06 pg/ml in controls, P = 0.000), folic acid (6.22 ± 2.46 ng/ml in cases vs. 8.49 ± 4.18 ng/ml in controls, P = 0.01), and biotin (252.71 ± 18.79 pg/ml in cases vs. 266.47 ± 30.44 pg/ml in controls, P = 0.013) levels were significantly lower in cases as compared to the controls. In view of the dark hair and many prevailing myths, premature canities is a significant problem in Asians with profound psychosocial impact.

In a study of subjects presenting ... Another showed no significant difference in vitamin B12 and folate levels and hair loss.19 Folate and B12 may have an effect on hair color, as a case-control study of 52 subjects in India with premature greying (defined as greying occurring ...

Folic acid with b12 - ANTI GRAY ... for women and men of all ages. This herbal supplement may be useful to help hair keep its youthful appearance and bring hair back to its natural color....

September 23, 2025 - B12 works synergistically with folate, biotin, and vitamin D to promote hair growth and pigmentation. A balanced nutrient intake amplifies benefits, supporting overall hair health.

June 1, 2022 - Exercises for Seniors: Tips for Core, Balance, Stretching See Slideshow · Premature graying may be due to various reasons, such as: Vitamin deficiencies, such as B12, biotin, or folate ...

A case–control study was conducted on 52 Indian subjects aged < 20 years with premature canities (graying of the hair), with a matched control for each patient. The authors assessed and compared biotin, folic acid and vitamin B12 levels in both groups. The results showed a deficiency of vitamin B12 and folic acid in the patients evaluated and lower levels of biotin without any obvious biotin deficiency in the cases [40]. Folate is another water-soluble B vitamin and includes naturally occurring food folate and folic acid (fully oxidized monoglutamate).

An optimal hair growth potential is considered to exist when specific parameters for biochemical variables are operating. These include red blood cell and serum folate concentrations within the normal range, serum vitamin B12 levels between 300 and 1000 ng/L, hemoglobin levels greater than 13.0 g/dL, and serum ferritin concentrations of 70 ng/mL or greater.

April 15, 2018 - Vitmain B12 is part of the B complex group. Its essential for hair growth and lack of it can cause hair loss. Causes and treatments are...

3 weeks ago - "At this time there is no scientific evidence that taking vitamins such as vitamin B12, copper, and folate, among others, can reverse gray hair," Dr. Shaver says. "Deficiencies in these vitamins, while rare in normal Western diets, have been ...

June 17, 2025 - The connection between B12 deficiency and premature greying has been documented in multiple studies, showing that adequate B12 levels help maintain natural hair pigmentation and support strong hair growth.

April 18, 2022 - Through supplementation of B vitamins we assure ourselves that we will receive thiamine (B1), riboflavin (B2), niacin (B3), pantothenic (B5), vitamin B6, biotin (B7), folate, and vitamin B12. B vitamins help enzymes in our bodies function properly while also encouraging healthy new cell turnover throughout your body. ... B vitamins do help in hair growth by encouraging healthy cell rejuvenation through abundant red blood cells which naturally support your hair follicles.

January 3, 2025 - Unfortunately, there is no scientific evidence to suggest that increasing vitamin B12 intake can reverse existing gray hair. Hair that has already lost its pigment is unlikely to regain its natural color.

June 8, 2022 - A published literature review suggested ... B vitamin deficiencies—specifically biotin, folate, niacin, riboflavin and B12 may lead to hair loss....

May 22, 2019 - Unless you’re willing to dye to your hair, you can’t restore hair that’s already gone gray to its former color. However, you may be able to preserve the rest of your color by making a few lifestyle changes. Read on to find out what you should add to your diet, whether supplements can ...

October 9, 2023 - Decreased hair follicle health - Vitamin B12 contributes to metabolising nutrients hair follicles need to stay healthy and productive. Lack of B12 can impair follicle function. Increased folate levels - B12 and folate balance each other in the body.

April 18, 2025 - When B12 levels are balanced, hair appears healthier, smoother, and more manageable. Melanin is the pigment responsible for your natural hair color, and B12 plays a role in its production.

November 3, 2023 - Our hair cells are rapidly growing, so they need regular supply of essential vitamin B12. A lack of B12 can slow hair growth and cause greying

May 24, 2023 - Research indicates that vitamin B12 deficiency can trigger premature graying because hair follicles aren't able to generate enough melanin, the pigment that lends color to our skin and hair(8).

A case of reversible generalized hyperpigmentation of the skin and nails with reversible premature gray hair due to vitamin B12 deficiency is reported. The cause of the vitamin B12 deficiency in this patient was pernicious anemia.