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View and buy high purity NU 9056 from Tocris Bioscience, a Bio-Techne brand. Inhibitor of KAT5 (Tip60). Cited in 6 publications.
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NU 9056
NU 9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor (IC50 values are < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively). Inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. Decreases proliferation of LNCaP cells; ind
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$188.00
NU9056 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an of 2 µM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells. - Mechanism of Action & Protocol.
Histone Acetyltransferase Inhibitor VIII, NU9056 - Calbiochem - Find MSDS or SDS, a COA, data sheets and more information.
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Tip60 (KAT5) is a histone acetyltransferase (HAT enzyme) involved in multiple cellular processes including transcriptional regulation, DNA damage repair and cell signalling. In prostate cancer, aggressive cases over-express Tip60 which functions as an androgen receptor co-activator via direct ...