N3C is a national resource of real-world data that researchers are using to speed medical research.

Researchers are welcome to request access to the N3C Data Enclave, one of the largest, most secure clinical data resources for accelerating and collaborating on COVID-19 research. Users may also join or start an N3C Domain Team to help coordinate work with others.

The N3C marshals the NCATS-supported resources of CTSA Program hubs and the CD2H to speed research and clinical care efforts at local, regional and national levels. It also leverages an existing framework of collaborative informatics networks and NCATS-supported cloud resources.

The N3C COVID Data Enclave is a centralized, secure, national clinical data resource with powerful analytics capabilities that the research community can use to study COVID-19.

Register for access to the N3C Data Enclave and explore harmonized clinical data within a secure analytics platform. Researchers are welcome to request access to the N3C Data Enclave, a leading secure data resource designed to support and accelerate collaborative research across a wide range ...

The steps to access the N3C data include registering with the N3C, completing required training and submitting a Data Use Request within the N3C Enclave. For further assistance, contact the N3C Support Desk. Step 1: Determine if an Institutional Data Use Agreement has been executed.

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November 17, 2020 - Data analysis within the enclave is supported by both R and Python, the most widely used open-source platforms for statistical analysis and data science. Researchers requesting access to, or working within, the enclave are encouraged to assemble collaborative teams with diverse expertise in ...

The National Center for Advancing Translational Sciences (NCATS) has systematically compiled clinical, laboratory and diagnostic data from electronic health records to support COVID-19 research efforts via the National COVID Cohort Collaborative (N3C) Data Enclave.

N3C Domain Teams enable researchers with shared clinical questions surrounding COVID-19 to collectively analyze data within the N3C Data Enclave and collaborate more efficiently in a team science environment.

N3C is holding a 2-part virtual orientation to learn how to use the N3C Data Enclave. The sessions alternate week by week for ongoing access. To view upcoming sessions, see N3C Data Enclave Training Registration.

A Domain Team is where a researcher will attend meetings with clinicians that are in the same clinical domain or expertise. N3C Domain Teams enable researchers with shared interests to analyze data within the N3C Data Enclave and collaborate more efficiently in a team science environment.

September 2, 2022 - N3C gives researchers access to a large enclave of COVID-19 data related to the entire patient journey, including symptoms and outcomes.

August 17, 2020 - AbstractObjective. Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational

NIH has launched a centralized, secure enclave to store and study vast amounts of medical record data from people diagnosed with coronavirus disease nationwide.

February 11, 2025 - The National Clinical Cohort ... COVID Cohort Collaborative, represents one of the largest, most secure clinical data resources for accelerating research on COVID-19. Built from the collaboration among the NCATS-supported Clinical and Translational Science Awards (CTSA) Program hubs, N3C Clinical will house multiple virtual domain-specific research enclaves (N3C Cancer, ...

September 30, 2020 - Overview The National Center for Advancing Translational Sciences (NCATS) and the National Center for Data to Health (CD2H), in partnership with experts from Observational Health Data Sciences and Informatics (OHDSI), the National Patient-Centered Clinical Research Network (PCORNet), the Accrual ...

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The N3C has demonstrated that a multisite collaborative learning health network can overcome barriers to rapidly build a scalable infrastructure incorporating multiorganizational clinical data for COVID-19 analytics. We expect this effort to save lives by enabling rapid collaboration among ...

N3C is stewarded by the National ... Development Award Networks for Clinical and Translational Research (IDeA-CTR), and thousands of researchers from hundreds of participating institutions in the US and abroad. The N3C Data Enclave is a secure platform through which the ...