Dental caries, also known as tooth decay or cavities, is a chronic infectious disease where bacteria in the mouth metabolize sugars to produce acid, which dissolves the hard tissues of the teeth (enamel, dentin, and cementum). It is the most common noncommunicable disease worldwide, affecting approximately 2.5 billion people, and can lead to pain, tooth loss, and infection if left untreated.

The disease process involves a shift in oral bacteria that creates an acidic environment, causing demineralization that outpaces the tooth's natural remineralization ability. Key risk factors include a diet high in free sugars, inadequate fluoride exposure, poor oral hygiene, and conditions that reduce saliva flow.

Progression and Prevention

  • Stages: The condition progresses from initial-stage caries (reversible white spots) to moderate-stage (microscopic pits) and extensive-stage (visible cavities reaching the nerve).

  • Symptoms: Early stages are often painless, but advanced decay causes sensitivity to hot, cold, or sweet foods, pain, and potential abscess formation.

  • Prevention: Effective strategies include limiting free sugar intake to less than 10% of total energy (ideally 5%), brushing twice daily with fluoridated toothpaste, flossing, and regular dental check-ups.

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NCBI
ncbi.nlm.nih.gov › books › NBK551699
Dental Caries - StatPearls - NCBI Bookshelf
June 21, 2023 - Dental caries is a common chronic infectious resulting from tooth-adherent cariogenic bacteria, primarily Streptococcus mutans, which metabolize sugars to produce acid, demineralizing the tooth structure over time.
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CDC
cdc.gov › oral-health › about › cavities-tooth-decay.html
About Cavities (Tooth Decay) | Oral Health | CDC
October 17, 2024 - Cavities (also called tooth decay or dental caries) are one of the most common diseases people get and live with during their lifetime.1 Cavities are caused by the bacteria in your mouth that stick to your teeth.
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Epidemiology

The prevalence of dental caries in children in the UK has reduced dramatically over the past 5 decades[footnote 7]. This is generally attributed to the introduction of fluoride-containing toothpaste in the early 1970s[footnote 4]. Other factors such as changed social attitudes, access to dental care, developments in preventive dental materials, together with health promoting and clinical practices have also contributed to these changes over time. Yet dental caries, which is largely preventable, remains prevalent and inequalities are marked[footnote 8].

Surveys of oral health in adults within the UK[footnote 9] suggest that there are 3 cohorts in the population:

  • the oldest cohort, who have lost all their teeth, and wear complete dentures
  • a middle cohort, who retain most of their teeth, but do so largely because of the efforts of the dental profession who have restored and maintained teeth in those who grew up before fluoride toothpaste became widely available
  • the youngest cohort, many of whom are caries-free in their early years

In the immediate future, the number of edentulous (toothless) people will continue to fall. Therefore, more adults will enter older age with some or all of their natural teeth, many of which will be heavily restored. Dental caries is not just a disease of children and young people - new carious lesions can develop at any age. Dental professionals therefore need to be vigilant and take appropriate action to support all patients, irrespective of age, based on their dental caries risk.

Root caries is increasingly a cause for concern and lifelong coronal caries experience is a risk factor for root surface caries experience[footnote 10]. Root caries increases with age and among independently living older adults. Factors such as poor plaque control, xerostomia (dry mouth), coronal decay and having exposed root surfaces are indicators of risk[footnote 11].

Like many common chronic lifestyle-associated diseases, the prevalence of dental caries is linked with social and economic circumstances[footnote 12][footnote 13] and ethnicity, with the prevalence of dental caries higher in some ethnic groups. It is, however, recognised that there is a complex interplay between these determinants. While some of the variation in disease levels can be accounted for by deprivation (around 41% among 5 year olds)[footnote 12], it is not the only risk factor, and dental team members play an important role in identifying modifiable risks, and helping individuals to recognise and minimise these risks and enhance protective factors.

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gov.uk
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Chapter 4: dental caries - GOV.UK
Early detection and management pathways

Given that dental caries can be identified and is reversible at an early stage, lesions should be identified at an early stage and managed. There is no evidence that a specific dental recall interval influences dental caries development or progression.

The time between dental check-ups should be based on risk, as assessed by the clinician, working with patients (and where appropriate parents or guardians) and will be influenced by preventive care needed. The recall period will change across the life course[footnote 32][footnote 33], as shown in chapter 1. For example, in children it is good practice for the recall period to be set so that they can obtain optimal prevention through treatments such as the application of fluoride varnish.

For older adults in care homes, having an oral health assessment on entry to the care home is recommended in NG48 by NICE[footnote 29], supported by access to professional care on a regular basis. Given that these people will be at higher risk of most oral diseases and conditions, shortened recall periods are likely to be the norm.

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gov.uk
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Chapter 4: dental caries - GOV.UK
Introduction

Dental caries is one of the most prevalent non-communicable diseases nationally[footnote 1][footnote 2] and globally[footnote 3]. The disease is caused by dietary sugars that are broken down by micro-organisms in the biofilm on a tooth surface, which produces acids that, over time, demineralise tooth enamel[footnote 4][footnote 5].

The process of de- and re-mineralisation is dynamic[footnote 4]. In the early stages of the disease, dental caries can be reversed. However, when factors promoting demineralisation exceed those favouring remineralisation, dental caries progresses (unless checked) into dentine to a point where the tooth surface breaks down and ultimately a cavity forms[footnote 5].

Effective patient care involves first diagnosing the presence and recording the extent of disease, using contemporary dental caries management tools such as the International Caries Classification and Management System (ICCMS)[footnote 6]. The next step involves:

    encouraging a reduction of factors that cause demineralisation, notably sugar consumption enhancement of those factors favouring remineralisation, particularly the availability of fluoride and mineral ions

Effective patient care may be achieved by a combination of preventive actions taken by patients, patient carers and healthcare professionals, supported by higher-level actions that promote policies and active change to facilitate a less cariogenic social environment.

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gov.uk
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Chapter 4: dental caries - GOV.UK
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Cleveland Clinic
my.clevelandclinic.org › health › diseases › 10946-cavities
Cavities (Tooth Decay): Symptoms, Causes & Treatment
July 21, 2017 - A cavity is a hole, or area of decay, in your tooth. Cavities form when acids in your mouth erode (wear down) your tooth enamel — your tooth’s hard, outer layer.
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Acffglobal
acffglobal.org › home › for patients › what is caries?
What is Caries? - The Alliance for a Cavity-Free Future
July 4, 2019 - Dental Caries is the scientific name for the disease process which can lead to tooth decay and cavities. How does it occur? Our mouths are home to many different types of bacteria, which, when we are healthy, are in balance.
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YouTube
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CARIES DENTAL.🦷🦠 - YouTube
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Published   April 14, 2022
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WHO
who.int › home › newsroom › fact sheets › detail › sugars and dental caries
Sugars and dental caries
August 14, 2025 - Dental caries affects all age groups, and can start with the eruption of the first teeth (deciduous teeth). The condition increases in prevalence in adulthood. In children, dental caries often leads to absence from school.
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PubMed Central
pmc.ncbi.nlm.nih.gov › articles › PMC9831703
Dental Caries and Its Management - PMC
In recent years, the management of dental caries has evolved significantly. Caries prevention, early detection, and a diagnosis based on risk indicators and risk factor assessments are the most current practical approaches. Furthermore, as proposed in minimally invasive dentistry, the new management approaches preserve healthy tissue and maintain pulp vitality.
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YouTube
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¿Qué es Caries Dental ? | Oral B LT - YouTube
La Caries es la disolución del tejido dental causado por la multiplicación de bacterias debido a la ingesta de azucares, la mala higiene dental o la incorrec...
Published   May 13, 2016
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Wikipedia
en.wikipedia.org › wiki › Tooth_decay
Tooth decay - Wikipedia
2 days ago - Tooth decay, also known as caries, is the breakdown of teeth due to acids produced by bacteria. The resulting dental cavities may be many different colors, from yellow to black. Symptoms may include pain and difficulty eating.
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GOV.UK
gov.uk › home › health and social care › public health › health improvement › oral health › delivering better oral health: an evidence-based toolkit for prevention
Chapter 4: dental caries - GOV.UK
September 10, 2025 - Dental caries is one of the most prevalent non-communicable diseases nationally[footnote 1][footnote 2] and globally[footnote 3]. The disease is caused by dietary sugars that are broken down by micro-organisms in the biofilm on a tooth surface, ...
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Mayo Clinic
mayoclinic.org › diseases-conditions › cavities › symptoms-causes › syc-20352892
Cavities and tooth decay - Symptoms and causes - Mayo Clinic
November 30, 2023 - These areas in the hard surface of your teeth are tiny openings or holes due to damage from tooth decay. This can lead to pain, infection and tooth loss.
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Colgate
colgateprofessional.com.au › home › patient education › dental caries (decay)
Dental Caries (Decay)
Dental caries is the medical term for tooth decay or cavities. It is caused by bacterial acids dissolving the tooth enamel and dentine.They accumulate (along with saliva, food particles and other natural substances) on the surface of the teeth ...
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Smiles for Life Oral Health
smilesforlifeoralhealth.org › home › dental caries
Dental Caries | Smiles for Life Oral Health
December 9, 2024 - Dental caries is the most common chronic disease of childhood from ages 6 to 19.
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Muscaro and Martin Dentistry
muscaroandmartinidentistry.com › dental-caries-and-their-causes
Dental Caries and Their Causes
September 20, 2023 - Cavities, or the disease known as dental caries, are caused by an imbalance of the bacteria in your mouth. Several things contribute to one’s risk for dental caries, such as lack of saliva, diet, bacteria, genetics and pH.
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Johns Hopkins Medicine
hopkinsmedicine.org › health › conditions-and-diseases › tooth-decay-caries-or-cavities-in-children
Tooth Decay (Caries or Cavities) in Children | Johns Hopkins Medicine
September 9, 2024 - Tooth decay is the breakdown or destruction of tooth enamel, the hard outer surface of a tooth. Tooth decay can lead to cavities, also called dental caries. These are holes in the teeth. Cavities can get bigger with time if left untreated.
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ScienceDirect
sciencedirect.com › science › article › abs › pii › S0140673607600312
Dental caries - ScienceDirect
January 4, 2007 - Dental caries, otherwise known as tooth decay, is one of the most prevalent chronic diseases of people worldwide; individuals are susceptible to this disease throughout their lifetime. Dental caries forms through a complex interaction over time between acid-producing bacteria and fermentable carbohydrate, and many host factors including teeth and saliva.
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Radiopaedia.org
radiopaedia.org › articles › dental-caries
Dental caries | Radiology Reference Article
March 20, 2017 - As a result of ever-increasing unsanctioned scraping by bots, we have instituted a challenge designed to keep them out, and make sure real users get the best experience possible · If you're not a bot, you shouldn't see this error. If it persists, please contact [email protected] and we'll ...
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Johns Hopkins Medicine
hopkinsmedicine.org › health › conditions-and-diseases › tooth-decay-caries-or-cavities
Tooth Decay (Caries or Cavities) | Johns Hopkins Medicine
Tooth decay is the disease known as caries or cavities. It's caused by certain bacteria in the mouth that thrive on sugars and refined carbohydrates and make acids as a side effect.
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Theoralhealthcenter
theoralhealthcenter.com › home › glossary › what are dental caries?
What Are Dental Caries? - Oral Health Center • Dentist Westerville OH
September 8, 2025 - Dental caries are permanently damaged areas in teeth that form holes or cavities. Also called tooth decay, dental caries are caused by bacteria that produce acids, which erode tooth enamel over time.