Hyperviscosity syndrome (HVS) is an oncologic emergency that classically presents with the triad of neurological deficits, visual changes, and mucosal bleeding. Elevated blood viscosity results from either red blood cell shape deformity or a pathological increase in serum proteins, red blood ...

August 24, 2023 - Hyperviscosity syndrome occurs when blood thickens so much that it doesn’t flow freely through blood vessels. This serious condition requires timely treatment.

April 27, 2025 - Learn what hyperviscosity is, what causes it, its symptoms, and how to treat it.

The hyperviscosity syndrome is the symptom and sign complex of abnormal levels of consciousness (inattention, drowsiness, stupor, coma, delirium), funduscopic changes characterized by venous engorgement (“sausage veins”), retinal hemorrhages and exudates, blurred vision, and headache The ...

3 weeks ago - Normal plasma viscosity is between ... evidence of their underlying disorder. Those with myeloma will typically display a rouleaux formation on a peripheral smear and a large globulin gap, indicative of a significant paraprotein load....

August 26, 2024 - Signs and Symptoms of High Blood Viscosity High blood viscosity often flies under the radar, but there are some red flags to watch out for. Symptoms can include fatigue, chest pain, shortness of breath, and frequent headaches. If you're experiencing these symptoms, it could be a sign of an ...

May 15, 2018 - Hyperviscosity syndrome is a condition in which blood is unable to flow freely through the arteries. This condition is most common in infants and children and can affect their growth by reducing blood flow to the vital organs. Read more about the symptoms and treatment of hyperviscosity syndrome.

Confusion and mental status changes result from the increased viscosity of the blood and decreased cerebral blood flow. This sludging leads to segmental dilatation of retinal veins and retinal hemorrhages.

Blood viscosity is increased by elevated concentrations of acute phase reactants and hypergammaglobulinemia in inflammation. These increase blood viscosity by increasing plasma viscosity and fostering erythrocyte aggregation. Blood viscosity is ...

September 1, 2023 - When blood becomes too thick, it can lead to clots and other complications. Here, learn more about why it happens and the effects.

Whole-blood hyperviscosity is seen in patients with extreme elevation of the red cell and white cell count. Phlebotomy of patients with primary and secondary elevation of the red cell count is a well-established therapy. Subjects: Clinical Trials and Observations, Lymphoid Neoplasia, Multiple ...

This can cause red cells to stick together and form chains of several cells (rouleaux formation) within the microcirculation, which increases the blood viscosity. Because of the high interaction between the elements of blood when it is not flowing, a driving pressure significantly greater than ...

September 12, 2024 - Polycythemia vera is a rare blood disorder in which there is an increase in all blood cells, particularly red blood cells. The increase in blood cells makes your blood thicker. This can lead to strokes or tissue and organ damage.

In patients with borderline hypertension, total peripheral resistance (TPR) is either elevated or abnormally related to cardiac output. Since blood viscosity is one determinant of TPR, we compared various components of blood viscosity in 25 patients with borderline hypertension and 25 normal ...

Increased blood viscosity reduces blood flow and elevates vascular resistance in the cardiovascular system. The aim of this study was to elucidate how blood viscosity could affect renal function and eventually contribute to renal damage in essential hypertensives (EHT).

January 23, 2025 - Blood viscosity is determined by red blood cells and protein components in plasma. Measuring blood viscosity is highly valuable in assessing thrombotic disorders.

Blood viscosity is an important determinant of local flow characteristics, which exhibits shear thinning behavior: it decreases exponentially with increasing shear rates. Both hematocrit and plasma viscosity influence blood viscosity. The shear ...

The hemodynamic milieu differs throughout the vascular tree because of varying vascular geometry and blood velocities. Accordingly, the risk of turbulence, which is dictated by the Reynolds and Dean numbers, also varies. Relatively high blood ...

Hyperviscosity syndrome (HVS) is a condition seen in several hematologic disorders characterized by increased blood viscosity leading to impaired microvascular flow and tissue hypoperfusion.