Amino Acids - It has been hypothesized that the dietary sweetener aspartame (L-aspartyl-L-phenylalanine methyl ester) might promote seizures and this hypothesis has been argued in the published...

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Although aspartame is widely used, and generally considered safe, there is evidence that it has an effect on monoamine metabolism which could theoretically lower seizure threshold.

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Studies in children to evaluate ... inducing seizures, with a particular focus on airline pilots. However, studies on adults and children have found no association between aspartame and seizure activity....

The claim that aspartame is associated with an increased risk of epilepsy is based on the anecdotal reports of individuals who happened to experience their first seizure soon after consuming an aspartame-containing food or beverage. This is not evidence of causation, but a temporal relationship ...

June 11, 2013 - Roberts said, “Tell them Betty!” I explained to the professor that aspartame is in thousands of products and the 50% phenylalanine lowers the seizure threshold. Even pilots are having seizures in the cockpits of commercial airliners.” ...

March 11, 2019 - BOSTON — A new report suggests that NutraSweet might trigger epilepsy in some susceptible people and recommends that doctors question seizure victims about their consumption of the popular artificial sweetener.

An association has recently been proposed between seizure promotion and consumption of the phenylalanine-containing artificial sweetener aspartame. Since consumption of aspartame, unlike dietary protein, can elevate brain phenylalanine, and ...

August 3, 2005 - Mean plasma phenylalanine (Phe) ... μCM).Results suggest that aspartame, in acute dosage of ε50 mg/kg, is no more likely than placebo to cause seizures in individuals who reported that their seizures were provoked by aspartame ...

May 3, 2004 - Monitoring of consumer complaints ... people with epilepsy have been published. Current evidence suggests that present consumption of aspartame does not induce brain damage, nor does it provoke seizures....

Seizure facilitation has been proposed as a possible adverse effect of dietary consumption of aspartame. The conversion of this sweetener to phenylalanine and aspartate in the gastrointestinal tract, and subsequent absorption, elevates plasma ...

March 1, 1993 - S. M. Gillespie, Aspartame has no effect on seizures or epileptiform discharges in epileptic children, Annals of Neurology, 35, 1, (98-103), (2004).https://doi.org/10.1002/ana.410350115

June 27, 2017 - Robert Cohen, a private citizen ... Cohen's personal theory: the milk-based formula in which the monkeys were served their Aspartame in this study is a key link why the brain seizures were suffered....

March 13, 2015 - Rather than speculating, I went to the source: science and scholarly research. In 1994, neurologists said there was no correlation between aspartame and seizure activity.

The effects of aspartame (L-aspartyl-L-phenylalanine methyl ester; APM) on the neurological status of children with well-documented seizures were examined in a randomized, double-blind, placebo-controlled, crossover study. We report on 10 children (5 boys, 5 girls, ages 5-13 yr) who were tested for …

June 1, 1992 - In support of the FDA decision ... adolescents showed that there were no clinically significant differences documented between the children taking aspartame and those taking sucrose for a 13 week period, regardless of age between ...

October 8, 2004 - No differences were noted for the ... after APM). Our findings indicate that, in this group of vulnerable children, APM does not provoke seizures. 1 Wurtman RJ. Aspartame: possible effect on seizure susceptibility....

November 26, 2009 - And, after receiving some 10,000 consumer complaints, the FDA compiled a list of 92 symptoms linked to aspartame — including death. WHY? Because aspartame attacks your body at the cellular level so it can negate all kinds of medications Americans take, including antidepressants, Coumadin, cardiac drugs, hormones, insulin, vaccines, and many others. In short, it is a deadly neurotoxic drug masquerading as a harmless additive. ... Thanks. I am becoming more and more concerned about the relationship between diet and seizures.

Aspartame promotes grand mal seizures, say health experts