Lowering blood cholesterol levels protects atherosclerosis. It was shown that functional foods such as vegetables, fruit fibers, fish oil, etc. have hypocholesterolemic effects and inhibit and suppress fat absorption and in vivo cholesterol synthesis (Carlos & Ferrari, 2017).

March 10, 2026 - In the elderly, low cholesterol may confer a health risk that may not be offset by the beneficial effects of cholesterol lowering. Similarly, for elderly patients admitted to hospital, low cholesterol may predict short-term mortality. The prevalence of hypocholesterolemia in the elderly ranges ...

August 23, 2022 - There has been some evidence that hypocholesterolemia can cause depression, suicidal ideation, and other effects on your mood or behavior.

Cholesterol biosynthesis enzyme HMG-CoA reductase is the target of most of the hypocholesterolemic drugs since it is the rate-limiting enzyme. However, myositis, gastrointestinal symptoms, pharyngitis, and pain are commonly associated side effects with these types of drugs.

Certain high-fiber foods have substantial hypocholesterolemic effects. These effects are related principally to the water-soluble fiber content of these foods (Jenkins et al., 1975; Anderson and Chen, 1979; Aro et al., 1984; Jenkins et al., 1980). Diets supplemented...

January 28, 2026 - Hypocholesterolemia may lead to mild liver dysfunction or fatty liver disease. You may also have problems with your eyes, brain, liver, muscles or bones. This comes from not having enough vitamin A, D, E or K in your body.

This is the reason that hypocholesterolemic drugs (3-hydroxy-3-methylglutaryl coenzyme A [HMG-CoA] reductase inhibitors or “statins”) have been associated with a lower risk of BPH and prostate cancer.9 There is limited evidence at this time to use these drugs to lower the risk of BPH, but ...

Each common variant is individually associated with marginally depressed levels of LDL cholesterol, but cumulatively these small effects add up to produce a potentially large effect. Polygenic susceptibility has also been captured in some cases of monogenic hypocholesterolemia and may explain some of the heterogeneity among cases with a common monogenic basis [Citation94].

November 23, 2009 - Soluble dietary fibers, such as pectin, are known to have hypocholesterolemic effects and are therefore considered important factors in reducing the risk of coronary heart disease [41]. In this study, algal products were as effective as, or more effective than, pectin in lowering plasma cholesterol levels and preventing the accumulation of cholesterol in the liver.

Nishimura S. Hypocholesterolemia in patients with polycy- ... Muldoon MF, Kritchevsky SB, Evans RW, Kagan VE. Serum · total antioxidant activity in relative hypo- and hypercholester- ... Iribarren C, Reed DM, Chen R, Yano K, Dwyer JH. Low · serum cholesterol and mortality. Which is the cause and · which is the effect?

February 6, 2024 - Google Scholar Interestingly, we found in the UKBB cohort that the increased risk of hepatic complications persists in the HBL group after excluding the first 5 years of follow-up. Importantly, the fact that the incidence of hepatic complications increases when LDL-C concentration decreases (5th vs. 1st percentile) also supports a direct role for hypocholesterolemia in the pathophysiology of liver complications.

May 12, 2026 - Low cholesterol (hypocholesterolemia) is almost never harmful. But sometimes, very low cholesterol levels can be a sign of another health issue.

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The researchers postulated the hypocholesterolemic action of VAO was due to its high levels of phytosterols and MUFA. Phytosterols, particularly β-sitosterol, play an important role in inhibiting the intestinal cholesterol absorption (Hernandez, 2016; Jesch & Carr, 2017). Dietary intakes of ...

October 18, 2010 - Hypocholesterolemia is characterized by serum total cholesterol that is lower than the 5th percentile for age and sex, or the cut-off value which predicts the adverse prognosis by epidemiological study. Unlike hypercholesterolemia, physicians pay less attention to the morbidity, causes and consequences of hypocholesterolemia in clinical practice.

August 14, 2025 - Hypocholesterolemic effect, according to the provided text, consistently refers to the ability of various substances to lower cholesterol levels in the bloodstream.

Hypocholesterolemia is the presence of abnormally low (hypo-) levels of cholesterol in the blood (-emia).

Patients with primary hypobetalipoproteinemias may manifest a variety of symptoms and signs affecting several organs (steatorrhea, neurological and ophalmological symptoms, non-alcoholic fatty liver disease) or be asymptomatic. Understanding hypocholesterolemia and the underlying molecular basis is of crucial importance since this may provide new insights in the treatment of hypercholesterolemia and cardiovascular disease.

May 1, 2010 - This suggests that HPMC supplementation affected both cholesterol and bile acid synthesis. Our data confirm that altered hepatic expression of lipid metabolism-related genes, possibly due to modulation of fecal bile acid excretion and intestinal cholesterol absorption, contributes to the lipid-lowering effects of HPMC.