September 23, 2021 - If you’ve got questions about oxytocin—what it is, what it does, how it feels—you’ve come to the right place. We’re going to answer your many Qs right now, with help from top docs.

We addressed this limitation by ... ToM, and its ability to remediate the neurophysiological abnormalities underlying ToM deficits in schizophrenia. fMRI studies examining oxytocin’s neurophysiological effects in schizophrenia have focused on emotional cue perception, revealing that oxytocin attenuates activity in the amygdala [25], inferior ...

This installment of the Windows to the Brain series offers an overview of oxytocin's many and varied effects, sites of action in the brain, and stimuli that are implicated in its actions. These include response to infant behavior, such as laughing or crying, “falling in love,” and abandonment.

Oxytocin (OT) is a neuroactive peptide that influences the processing of fearful stimuli in the amygdala. In the central nucleus of the amygdala, the activation of OT receptors alters neural activity and ultimately suppresses the behavioral response to a fear conditioned stimulus.

The amygdala reveals enhanced reactivity to fearful eye whites, even when they are backwardly masked by a neutral face and therefore processed with limited visual awareness. In our fMRI study, we investigated whether this effect is indeed associated with fear detection within the eyes of the ...

Oxytocin (OXT), produced and secreted in the paraventricular nucleus and supraoptic nucleus of magnocellular and parvocellular neurons. The diverse presence and activity of oxytocin suggests a potential for this neuropeptide in the pathogenesis and treatment of stress-related neuropsychiatric ...

This review summarizes and critically ... of the oxytocinergic system on opioid addiction‐related processes, as well as the effects of opioids on the OT system at different stages of the addiction cycle. The mechanisms underlying the effects of OT on opioid addiction, including OT' interaction with the monoaminergic, glutamatergic, opioidergic systems and its effect on the amygdala, the ...

The neuropeptide oxytocin plays an essential role in regulating social behavior and has been implicated in a variety of human cognitive processes in the social domain, including memory processes. The present study investigates the influence of oxytocin ...

Oxytocin (OT) knock-out mice fail to recognize familiar conspecifics after repeated social exposures, despite normal olfactory and spatial learning abilities. OT treatment fully restores social recognition. Here we demonstrate that OT acts in the ...

Social deficits are key hallmarks of the Clinical High Risk for Psychosis (CHR-P) state and of established psychotic disorders, and contribute to impaired social functioning, indicating a potential target for interventions. However, current treatments do not significantly ameliorate social ...

Oxytocin is a recombinant hormone used to induce or strengthen uterine contractions in pregnant women to aid in labor and delivery or to control postpartum bleeding.

Oxytocin (OT) plays a pivotal role in a variety of complex social behaviors by modulating approach-avoidance motivational tendencies, but recently, its social specificity has been challenged. Here, a randomized, double-blind, placebo-controlled ...