Diabetic Peripheral Neuropathy is one of the most important and significantly prevalent microvascular complications of Diabetes Mellitus. Pyridoxine i…

May 1, 2024 - Vagus Nerve Stimulation could be your key to better health and could lead to greater happiness and fulfillment in all areas of your life

August 12, 2024 - Learn why vitamin B6 is important in preventing anemia, improving your mood, protecting your heart and more. Plus, learn what foods are high in this essential vitamin.

July 12, 2023 - Medicines Safety Update - Information for health professionals

Dysautonomia has substantially impacted acute COVID-19 severity as well as symptom burden after recovery from COVID-19 (long COVID), yet the underlying causes remain unknown. Here, we hypothesized that vagus nerves are affected in COVID-19 which might ...

Sinus node dysfunction is a multifaceted disorder with variable manifestations, the prevalence of which increases with age. In a specific group of patients, ...

High doses of vitamin B6 can lead to neuropathy instead of helping nerve pain heal. Why do these supplements backfire this way?

The generation of properly functioning circuits during brain development requires precise timing of cell migration and differentiation. Disruptions in the developmental plan may lead to neurological and psychiatric disorders. Neocortical circuits ...

Discover and learn more about the structure, location, and functions of the vagus nerve as well as the clinical significance of its damage or injury.

March 26, 2024 - Ross Hauser, MD Anything that the body physiological knows is stressful will eventually damage the vagus nerve; likely anything the body physiological knows is there to give it health will strengthen the vagus nerve. Our bodies are smarter than our ego-centered lifestyles and that is, in large ...

Neurological degeneration after neuroinflammation, such as that resulting from Alzheimer’s disease (AD), stroke, multiple sclerosis (MS), and post-traumatic ...

Sinus node dysfunction is a multifaceted disorder with variable manifestations, the prevalence of which increases with age. In a specific group of patients, excessive vagal activity may be the sole cause for this condition. These patients are characterized ...

Polyneuropathy related to decreased levels of Vitamin B6 are well known. In contrast, the association between elevated levels of pyridoxine and neuropathy is not well described. This study is a retrospective review of patients in our neuromuscular clinic that were found to have elevated B6 levels.

Introduction: Vitamin B6 is a water-soluble vitamin that is naturally present in many foods and is accessible in many dietary supplements. The three natural forms are pyridoxine, pyridoxal, and pyridoxamine. Both vitamin B6 deficiency and high B6 intake have been described as risk factors for ...

Depression is a worldwide disease causing severe disability, morbidity, and mortality. Despite abundant studies, the precise mechanisms underlying the pathophysiology of depression remain elusive. Recently, cumulate research suggests that a disturbance ...

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The effects of different levels of dietary pyridoxine (1.0, 1.2, 1.4, and 20.0 mg/kg diet) fed to dams during growth, gestation and lactation on myeli…

August 7, 2024 - Vitamin B6 Deficiency and Dependency and Nutritional Disorders - Learn about from the Merck Manuals - Medical Professional Version.

March 7, 2023 - The vagus nerve is more important than most people realize. Learn about the effects of vagus nerve dysfunction and how to promote vagus nerve healing.