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Reddit
reddit.com › r/transhumanism › intra-body molecular communication via blood- tissue barrier for internet of bio-nano things (iobnt)
r/transhumanism on Reddit: Intra-Body Molecular Communication via Blood- Tissue Barrier for Internet of Bio-Nano Things (IOBNT)
April 11, 2025 -

In the Intra-body nano networks, the bio-nanomachines enter the body through injection into the blood and then navigate autonomously throughout the body to reach the blood capillary network. The blood tissue barrier inside the body forms the main communication pathway for molecular information exchange between the nanomachines as well as between the intra-body nano network and the Bio-Cyber interface in the IoBNT network. Watch the video to learn more about how the Brain Tissue Barrier, the Blood Brain barrier, the Intra-body nanonetwork, and The Bio-Cyber interface all work together in this research in mimicking biology for nano communication.

https://opus.lib.uts.edu.au/handle/10453/159605

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YES I did use chatGPT to parse the paper: It's 100% simulation and modeling—no wet lab, no hardware, no live implants. Just molecules in silico. Here's what they did do: Built a COMSOL Multiphysics numerical model of molecule transport across capillary walls. Developed a custom MATLAB particle simulator to validate the model—tracks molecule-by-molecule movement under diffusion, flow, degradation, and capillary permeability. Compared the two to ensure the math holds up. Ran a bunch of simulations changing parameters (flow speed, distance, emission duration, permeability, etc.) to see how they affect the molecular "signal" received. What they did not do: No experiments with nanorobots or nanomachines. No animal or human testing. No physical bio-cyber interface prototypes. No integration with actual sensors or drug delivery systems.It's 100% simulation and modeling—no wet lab, no hardware, no live implants. Just molecules in silico. It's a toolbox contribution: if someone were building a real nano-drug-delivery system, this could guide where to place the transmitter, how fast to release the drug, how to interpret signals, or even how to design the capillary interface. Conclusion: Its a modeling tool, nothing more.
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Video credit to ByrdTurd86. Hoping to share more research papers and “cutting edge,” or lesser known, developments. Hopefully this is okay with mods of this subreddit! Thank you in advance. CRISPR-Enabled Graphene-Based Bio-Cyber Interface Model for In Vivo Monitoring of Non-Invasive Therapeutic Processes
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ScienceDirect
sciencedirect.com › science › article › abs › pii › S0010482521005011
Securing Bio-Cyber Interface for the Internet of Bio-Nano Things using Particle Swarm Optimization and Artificial Neural Networks based parameter profiling - ScienceDirect
July 31, 2021 - Internet of Bio-Nano Things (IoBNT) is an emerging ICT paradigm that defines a set of networks for communication between natural and artificial nanoscale entities like nano biosensors or genetically engineered bacteria, and Information and Communication (ICT) based applications integrated with the Internet infrastructure Akyildiz, Pierobon, Balasubramaniam and Koucheryavy [1]. IoBNT aims for connectivity and control over non-conventional domains such as the human body.
Discussions

How do you see the internet of bodies and the internet of bio-nano things playing out?
That’s a lot of jargon and fancy words. This will all cost money to develop, licence and implement. Try explaining this to someone without any real biology or technology knowledge. If they don’t really see the point of this then no investor is going to see the point either. What is connecting every human cell to the internet even meant to accomplish?! More on reddit.com
🌐 r/biology
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February 13, 2025
The Internet of Bio-Nano Things - Smart Computing in the Human Body
Medical devices controlled by bluetooth. This might be the worst idea I have ever heard More on reddit.com
🌐 r/transhumanism
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April 15, 2025
How many years away is the internet of bio-nano things (loBNT) and who will have first access?
With the current dominant economic system on earth being capitalism, it’s probably a good thing this is currently in the “emerging framework” pipe-dream phase. Can you imagine if Elon musk wasn’t lying when he said they would cure all neurological illnesses “in about 2 years” with neuralink? People would have to pay a subscription service to use their own CNS. More on reddit.com
🌐 r/bioengineering
6
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February 14, 2025
Intra-Body Molecular Communication via Blood- Tissue Barrier for Internet of Bio-Nano Things (IOBNT)
YES I did use chatGPT to parse the paper: It's 100% simulation and modeling—no wet lab, no hardware, no live implants. Just molecules in silico. Here's what they did do: Built a COMSOL Multiphysics numerical model of molecule transport across capillary walls. Developed a custom MATLAB particle simulator to validate the model—tracks molecule-by-molecule movement under diffusion, flow, degradation, and capillary permeability. Compared the two to ensure the math holds up. Ran a bunch of simulations changing parameters (flow speed, distance, emission duration, permeability, etc.) to see how they affect the molecular "signal" received. What they did not do: No experiments with nanorobots or nanomachines. No animal or human testing. No physical bio-cyber interface prototypes. No integration with actual sensors or drug delivery systems.It's 100% simulation and modeling—no wet lab, no hardware, no live implants. Just molecules in silico. It's a toolbox contribution: if someone were building a real nano-drug-delivery system, this could guide where to place the transmitter, how fast to release the drug, how to interpret signals, or even how to design the capillary interface. Conclusion: Its a modeling tool, nothing more. More on reddit.com
🌐 r/transhumanism
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April 11, 2025
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ResearchGate
researchgate.net › publication › 273780747_The_internet_of_Bio-Nano_things
(PDF) The internet of Bio-Nano things
July 16, 2026 - The Internet of Bio-Nano Things (IoBNT) extends the Internet of Things into the biochemical domain of living systems through nanoscale bio-engineered devices that sense, actuate, and communicate primarily via molecular signalling. Eleven years after the founding vision of Akyildiz et al.
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ACM Computing Surveys
dl.acm.org › doi › 10.1145 › 3703448
The Internet of Bio-Nano Things with Insulin-Glucose, Security and Research Challenges: A Survey | ACM Computing Surveys
The Internet of Bio-Nano Things (IoBNT) is collaborative cell biology and nanodevice technology interacting through Molecular Communication (MC). The IoBNT can be accomplished by using the Information and Communication Theory (ICT) study of biological networks.
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HackerNoon
hackernoon.com › wtf-is-internet-of-bio-nano-thingsiobnt-and-how-secure-is-it-v62z32a5
WTF is Internet Of Bio Nano Things (IoBNT) and How Secure Is It? | HackerNoon
January 30, 2021 - Ian Akyildiz and his group members have coined the term "Bio Cyber terrorism" for IoBNT attacks in their pioneering work on IoBNT.Security mechanisms used for traditional networks demand high computation power which is beyond the capabilities ...
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Springer
link.springer.com › home › multimedia tools and applications › article
Internet of Bio-NanoThings privacy: securing a multi compartmental targeted cancer drug delivery scheme | Multimedia Tools and Applications | Springer Nature Link
March 4, 2024 - The data that support the findings of this study are available from the corresponding author upon reasonable request. ... Akyildiz I, Brunetti F, Blázquez C (2008) Nanonetworks: a new communication paradigm.
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Springer
link.springer.com › home › wireless personal communications › article
Biocyber Interface-Based Privacy for Internet of Bio-nano Things | Wireless Personal Communications | Springer Nature Link
May 26, 2020 - Wireless Personal Communications - The concept of Internet of bio-nano thing (IoBNT) arose from the need for Biological nanomachines to interconnect intra-body nanonetwork with the cyber Internet...
Find elsewhere
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arXiv
arxiv.org › abs › 2112.09249
[2112.09249] Internet of Bio-Nano Things: A Review of Applications, Enabling Technologies and Key Challenges
December 16, 2021 - View a PDF of the paper titled Internet of Bio-Nano Things: A Review of Applications, Enabling Technologies and Key Challenges, by Murat Kuscu and Bige D.
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ITU
itu.int › dms_pub › itu-s › opb › jnl › S-JNL-VOL2.ISSUE3-2021-A08-PDF-E.pdf pdf
INTERNET OF BIO‑NANO THINGS: A REVIEW OF APPLICATIONS, ENABLING TECHNOLOGIES
INTERNET OF BIO‑NANO THINGS: A REVIEW OF APPLICATIONS, ENABLING TECHNOLOGIES · Murat Kuscu1 and Bige Deniz Unluturk2
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MDPI
mdpi.com › 1424-8220 › 23 › 5 › 2807
Internet of Nano-Things (IoNT): A Comprehensive Review from Architecture to Security and Privacy Challenges
March 3, 2023 - In general, the IoNT infrastructure can be deployed by combining nanodevices with the IoT, sensor networks, cloud computing, and big data analytics [1,4]. The IoNT has spawned numerous new domains, including the Internet of Bio-Nano-Things (IoBNT) and the Internet of Multimedia Nano-Things (IoMNT), which can aid in the development and integration of sophisticated technologies in the healthcare and media and entertainment industries [4,17,22,23,24,25]. The IoMNT architecture includes nano-cameras and photodetectors, which are constructed on a nanoscale and are mostly employed in telecommunications.
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Reddit
reddit.com › r/biology › how do you see the internet of bodies and the internet of bio-nano things playing out?
r/biology on Reddit: How do you see the internet of bodies and the internet of bio-nano things playing out?
February 13, 2025 -

I've been learning about the internet of bio-nano things (loBNT), internet of bodies, and internet of everything.

Specifically, an idea l've seen referred to as the "cell to internet" paradigm, enabled by 6G. As in, human bodies being connected to the internet down to the cellular level, apparently one cell at a time.

I'm wondering how everyone sees this playing out? Who will get access first to connect their bodies to the internet? How many years away are we from intra body wireless nano networks?

I've also learned of a concept known as "IoBNT terrorism" where cells can be "reprogrammed” from a distance which could cause either sickness or death. How many years away are we from having to worry about "remotely reprogramming" cells?

Will people be able to opt out of the internet of bio-nano things?

Thanks for any insights!

https://ieeexplore.ieee.org/document/ 9022753

https://www.iotaustralia.org.au/2015/07/28/ iotnewsglobal/get-ready-for-the-internet-of-bio-nanothings/

https://teaching.eng.cam.ac.uk/content/ engineering-tripos-part-iib-427-internet-everything-2023-24

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ScienceDirect
sciencedirect.com › science › article › pii › S2590137024001365
A Biologically Inspired and Protein-Based Bio-Cyber Interface for the Internet of Bio-Nano Things - ScienceDirect
December 20, 2024 - In recent years, scientific progress in biotechnology and nanotechnology has led to new approaches and interdisciplinary collaborations in electrical and communication engineering, giving rise to the concept of the Internet of Bio-Nano Things (IoBNT) (Akyildiz et al., 2015) including a new communication paradigm called Molecular Communication (MC).
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Medical Design Briefs
medicaldesignbriefs.com › home › iomt
Building the Internet of Bio-Nano Things - Medical Design Briefs
January 17, 2024 - Researchers have developed a protocol that enables a molecular network with multiple transmitters. The interface of computer science and biology —the Internet of Bio-Nano Things (IoBNT) — promises to revolutionize medicine and healthcare.
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arXiv
arxiv.org › abs › 2304.03824
[2304.03824] Graphene and Related Materials for the Internet of Bio-Nano Things
April 7, 2023 - Abstract:Internet of Bio-Nano Things (IoBNT) is a transformative communication framework, characterized by heterogeneous networks comprising both biological entities and artificial micro/nano-scale devices, so-called Bio-Nano Things (BNTs), interfaced with conventional communication networks for enabling innovative biomedical and environmental applications.
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Umd
bbi.umd.edu › news › story › the-internet-of-bionano-things
The Internet of Bio-Nano Things | Brain and Behavior Institute
March 30, 2021 - University of Maryland (UMD) Fischell Department of Bioengineering (BIOE) alumni Jessica L. Terrell (Ph.D. ‘15; U.S. Army Research Laboratory [ARL]) and Tanya Tschirhart (Ph.D. ‘14; U.S. Naval Research Laboratory [NRL]) were first authors of the Nature Nanotechnology paper.
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arXiv
arxiv.org › abs › 2509.17227
[2509.17227] Hijacking Living Cells with Surface Engineering for the Internet of Bio-Nano Things
September 21, 2025 - Abstract:The Internet of Bio-Nano Things (IoBNT) promises to revolutionize healthcare by interfacing the cyber domain with the living systems at unprecedented resolution. Realizing this vision hinges on the development of Bio-Nano Things (BNTs), i.e., functional nodes capable of sensing, actuation, and communications within biological environments.
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arXiv
arxiv.org › abs › 2506.20589
[2506.20589] Communicating Smartly in Molecular Communication Environments: Neural Networks in the Internet of Bio-Nano Things
May 31, 2026 - Recent developments in the Internet of Bio-Nano-Things (IoBNT) are laying the foundation for innovative healthcare applications that envision a network of remotely coordinated nanodevices within the human body to monitor and actuate over potential diseases. However, interconnecting such nanodevices ...
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IEEE Xplore
ieeexplore.ieee.org › document › 7060516
The internet of Bio-Nano things | IEEE Journals & Magazine | IEEE Xplore
The Internet of Things (IoT) has become an important research topic in the last decade, where things refer to interconnected machines and objects with embedded computing capabilities employed to extend the Internet to many application domains. While research and development continue for general ...
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AIP Publishing
pubs.aip.org › aip publishing › apl mater. › perspectives
Graphene and related materials for the Internet of Bio-Nano Things | APL Materials | AIP Publishing
August 7, 2023 - Central to the IoE vision, which draws inspiration from the vast connectivity and diverse networking characteristics of the universe, is the emerging Internet of Bio-Nano Things (IoBNT) framework, which encompasses collaborative networks of Bio-Nano Things (BNTs).4 These networks consist of a diverse array of context-aware entities, including biological beings and artificial micro/nanoscale devices, such as engineered bacteria and nanosensors, that interact closely with their natural counterparts in complex biological environments.5 Leveraging the power of nanotechnology and biotechnology with communication and networking tools, IoBNT is poised to seamlessly bridge the digital and biological worlds in ways and at spatiotemporal resolutions that were previously inconceivable.