June 13, 2025 - Numerous research investigations have documented the benefits of Eriobotrya japonica, including its antioxidant, anti-inflammatory, antidiabetics, antitumor, hypoglycemic, anti-obesity, hepatoprotective and cardioprotective properties [1]. In ...

July 21, 2022 - Previous studies have confirmed ... herbal medicine to treat coughing caused by pulmonary inflammation, dyspnea due to asthma and cough, nausea caused by stomach disorders, restlessness, and thirst [28]. In this study, we ...

Conclusion: The findings demonstrate that E. japonica leaf extract at doses of ≥200 mg/kg significantly reduces body weight and improves lipid markers in HFD-fed rats. However, glycemic markers such as blood glucose and HbA1c were not ...

November 15, 2022 - Other beneficial physiological effects such as antioxidant, hepatoprotective, bronchodilatory, antitussive, and expectorant effects and tracheal smooth muscle relaxation, protection against myocardial ischemia injury, and improved cognitive activities have also been reported. High doses of E. japonica leaf extracts have been used in laboratory animals, and no side effects or toxicity-symptoms have been observed.

June 17, 2022 - Loquat (Eriobotrya japonica (Thunb.) Lindl.) is an evergreen tree native to China, which is introduced in many Mediterranean countries. As in many ancient medical systems, loquat leaves have been used in Moroccan traditional medicine to treat diabetes and its complications. This study aims to determine the nutritional and polyphenol composition and to evaluate the in vivo antidiabetic, and antihyperlipidemic properties and oral toxicity of a leaf aqueous extract (LLE) derived from loquat grown in Morocco.

March 29, 2025 - These results highlight the strong ... supplements or therapeutic candidates for managing oxidative stress, hyperglycemia, neurodegenerative diseases, and inflammatory disorders....

CCl4-treated rats that were given ... profiles. Thus, we conclude that Eriobotrya leaf extract and its fractions have a hepatoprotective effect against CCl4-induced hepatotoxicity in rats....

August 31, 2025 - Recent research reported inhibitory effects of Eriobotrya japonica leaf extracts on DPPH free radicals and α-amylase, α-glucosidase, and lipase enzymes. These enzymes were linked to the etiology of diabetes mellitus, obesity, and oxidative stress.

The evergreen subtropical tree Eriobotrya japonica Lindl (loquat) belongs to family Rosaceae (Younes & Sassine, 2016). Chinese folk medicine used loquat plant in the treatment of many ailments (Liu et al., 2016), consequently different scientific studies was made on loquat plant proven some of its bioactivities such as anti-tumor(Ito et al., 2002), treatment of bronchial asthma (Hirota & Suganuma, 2009), anti-inflammatory (Cha et al., 2011); (Selvamuthukumaran et al., 2020), antioxidant (Delfanian et al., 2015), anti-diabetes(Suhani & Soubhik, 2018), cardio-protective(Chiang et al., 2018), anti-hyperglycemia (Ahumada et al., 2017) and hepatoprotective (Shahat et al., 2018).

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Leaves of Eriobotrya japonica (LEJ) Lindl (Rosaceae) have been used as traditional medicines for lung and stomach diseases and have been found to be effective in chronic bronchitis, inflammation, asthma, low back pain and tumor.1–3,4 Studies have demonstrated that LEJ has anti-inflammatory ...

We investigated whether EJEE can regulate melanin production because melanin plays an essential role against UV-induced ROS production, EJEE has demonstrated potent anti-oxidant and anti-inflammatory activities [38, 39]. Recent studies have shown that hyperpigmentation is caused by various inflammatory skin disorders, such as eczema, and dermatitis [8, 9, 40, 41]. In this study, melanin content was significantly inhibited by EJEE at concentrations of 0.05 and 0.1%. Recently, Tan et al. [42] reported that the methanolic extract of Eriobotrya japonica leaf exhibits a significant dose-dependent inhibition of melanogenesis in B16 melanoma cells.

Although its exact etiology remains unidentified, it is believed to be caused by a combination of factors such as aging, inflammation, and hormonal imbalance. This study examined the effects of E. japonica leaf 50% ethanol extracts (EJE) on human prostate epithelial BPH-1 cells and a BPH rat model developed via testosterone propionate (TP) injection.

October 31, 2025 - Research suggests leaf extracts down-regulate inflammatory mediators like IL-6 and TNF-α in lung epithelial cells. Fruit pulp, rich in sugars and organic acids, acts more on the gut microflora, promoting bifidobacteria growth.

March 1, 2026 - Eriobotrya japonica Lindl, also ... weight reduction. In our present study, we validated the impact of E. japonica leaf extract on body weight, glycemic control, and lipid profile....

September 2, 2025 - Modern extracts concentrate bioactive triterpene acids (notably ursolic and oleanolic acids), flavonoids, and procyanidins that show anti-inflammatory, antioxidant, and immunomodulatory actions in laboratory and early human studies.

April 5, 2018 - Total sesquiterpene glycosides from Loquat (Eriobotrya japonica) leaf alleviate high-fat diet induced non-alcoholic fatty liver disease through cytochrome P450 2E1 inhibition