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Epa
epa.gov › sites › default › files › 2016-09 › documents › chloroform.pdf pdf
Chloroform
Website of the U.S. Environmental Protection Agency (EPA). EPA's mission is to protect human health and the environment.
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NCBI
ncbi.nlm.nih.gov › books › NBK201468
Chloroform: Acute Exposure Guideline Levels - Acute Exposure Guideline Levels for Selected Airborne Chemicals - NCBI Bookshelf
Data on the mechanism of toxicity and tumorigenicity of chloroform suggest that the tumorigenic response occurs at concentrations that cause cell death and proliferative cellular regeneration. Thus, a linear low-dose extrapolation for cancer risk might not be appropriate.
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NCBI
ncbi.nlm.nih.gov › books › NBK604204
Chloroform Toxicity - StatPearls - NCBI Bookshelf
Although chloroform toxicity is ... have indicated a potential correlation between both acute and chronic chloroform exposure and heightened risks of liver and kidney diseases, along with other health complications.[3]...
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CDC
wwwn.cdc.gov › TSP › ToxFAQs › ToxFAQsDetails.aspx
Chloroform | ToxFAQs™ | ATSDR
Exposure to chloroform can occur when breathing contaminated air or when drinking or touching the substance or water containing it. Breathing chloroform can cause dizziness, fatigue, and headaches. Breathing chloroform or ingesting chloroform over long periods of time may damage your liver ...
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CDC
wwwn.cdc.gov › TSP › PHS › PHS.aspx
Chloroform | Public Health Statement | ATSDR
Skip directly to site content · Agency for Toxic Substance and Disease Registration Agency for Toxic Substance and Disease Registration · Toxic Substances Portal
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Wisconsin
dhs.wisconsin.gov › chemical › chloroform.htm
Chloroform | Wisconsin Department of Health Services
March 30, 2023 - Chloroform is suspected of causing cancer. Liver and kidney tumors have been reported in laboratory animals. Any exposure to a cancer-causing chemicals may increase your risk of developing cancer.
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PubMed
pubmed.ncbi.nlm.nih.gov › 9356278
Chloroform mode of action: implications for cancer risk assessment - PubMed
The following points summarize the critical data: (1) a substantial body of data demonstrates a lack of direct in vivo or in vitro genotoxicity of chloroform; (2) chloroform induces liver and kidney tumors in long-term rodent cancer bioassays only at doses that induce frank toxicity at these ...
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NCBI
ncbi.nlm.nih.gov › books › NBK590753
Chloroform - 15th Report on Carcinogens - NCBI Bookshelf
The International Agency for Research on Cancer (IARC 1999) concluded that a causal relationship between cancer and chloroform could not be inferred, because of the use of indirect methods of assessing exposure, incomplete control for confounding by exposure to other water impurities or other risk ...
Find elsewhere
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State
health.state.mn.us › communities › environment › risk › docs › guidance › gw › chloroforminfo.pdf pdf
Chloroform and Drinking Water
Human health risk assessment is used to evaluate the effects of a chemical or substance (contaminant) on human health using the best available scientific information. The guidance values developed through the risk assessment process are used by government agencies, policymakers, and the public ...
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Gov
gov.uk › home › health and social care › public health › health protection › chemical and environmental hazards › chloroform: health effects, incident management and toxicology
Chloroform: general information - GOV.UK
August 6, 2024 - Chloroform is used in pesticide formulations, as a solvent and chemical intermediate in laboratories and industry, as a cleansing agent, in the production of dyes, in fire extinguishers and in the pharmaceutical and rubber industries.
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NCBI
ncbi.nlm.nih.gov › books › NBK208286
CHLOROFORM - Emergency and Continuous Exposure Limits for Selected Airborne Contaminants - NCBI Bookshelf
International Agency for Research on Cancer. 1972. Chloroform. In IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Volume 1. Lyon, France: International Agency for Research on Cancer.
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ScienceDirect
sciencedirect.com › science › article › pii › S0273230097911612
Chloroform Mode of Action: Implications for Cancer Risk Assessment - ScienceDirect
Risk assessment methodology, particularly pertaining to potential human carcinogenic risks from exposures to environmental chemicals, is undergoing in…
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Wikipedia
en.wikipedia.org › wiki › Chloroform
Chloroform - Wikipedia
2 weeks ago - While few studies have assessed the risks posed by chloroform exposure through drinking water in isolation from other THMs, many studies have shown that exposure to the general category of THMs, including chloroform, is associated with an increased risk of cancer of the bladder or lower GI tract.
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CDC
atsdr.cdc.gov › ToxProfiles › tp6-c1.pdf pdf
Toxicological Profile for Chloroform, Draft for Public Comment
ATSDR developed this Completed Exposure Pathway List to track the substances to which people have been exposed at hazardous waste sites. It was updated as part of the Priority List of Hazardous Substances for 2001.
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ScienceDirect
sciencedirect.com › topics › biochemistry-genetics-and-molecular-biology › chloroform
Chloroform - an overview | ScienceDirect Topics
Chloroform is only slightly soluble in water and evaporates quickly into surrounding air, increasing the risk of inhalation exposure [19,266,267]. In addition, chloroform persists for a long time in both water and air [266]. There are no natural sources of chloroform, but this contaminant enters ...
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Unl
unl.edu › cahoonlab › Chloroform MSDS.pdf pdf
Unl
The University of Nebraska–Lincoln is the flagship public research university in Nebraska, and is a member of the Big Ten Conference. Home of the Huskers.
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PubMed
pubmed.ncbi.nlm.nih.gov › 10717377
Risk assessment case study--chloroform and related substances - PubMed
Chlorine, used as an important disinfectant for drinking water, can react with naturally occurring organic matter to form chloroform, bromodichloromethane, chlorodibromomethane and bromoform. Chloroform and other trihalomethanes have been shown to increase tumours of the liver, kidney or large ...
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Miami
bionium.miami.edu › _assets › pdf › chloroform.pdf pdf
chloroform.pdf - Safety Data Sheet
In late 2012, The Dr. John T. Macdonald Foundation Biomedical Nanotechnology Institute of University of Miami (BioNIUM) was established at the University of Miami with the generous philanthropic support of $7.5 Million by the Dr. John T. Macdonald Foundation, with additional equivalent supporting ...