1 week ago - Hemp (Cannabis sativa) is the same species of plant as cannabis. Unlike cannabis, hemp contains very low levels of delta-9-tetrahydrocannabinol (THC). Both hemp and cannabis also contain cannabinoids such as cannabidiol (CBD), cannabidivarin (CBDV), cannabigerol (CBG), and others.

This review focuses on the potential therapeutic effects of cannabis and cannabinoids, as well as the acute and chronic toxic effects of cannabis use on various body systems. Keywords: Cannabis sativa, marijuana, hemp, cannabinoids, endocannabinoids, cannabinoid receptors, Δ-9-tetrahydrocannabinol (THC), therapeutics, toxicity, abuse

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To address this research question, it will be more appropriate to systematically analyse toxicity and safety data in a separate review, given the bulk of data and studies that were already included in this paper. There is a growing number of studies conducted on hemp and hemp-derived compounds, representing an increasing interest in this field of research. Most hemp-specific evidence is preliminary with insufficient high quality clinical evidence for any specific therapeutic indications. In addition to cannabinoids, a few non-cannabinoid bioactive compounds including protein hydrolysates and propionamides demonstrated some pharmacological potential which can be further explored.

May 2, 2026 - Under U.S. law, these plants are considered “industrial hemp” rather than marijuana. Throughout the rest of this fact sheet, we use the term “cannabis” to refer to the plant Cannabis sativa. Cannabinoids are a group of substances found in the cannabis plant.

January 25, 2025 - Evaluating full-spectrum Cannabis sativa extracts is even more complex since whole extracts and isolated phytomolecules do not act in the same way. Given the growing interest in cannabinoid-containing products for human use and the fact that most cannabis treatments utilize entire inflorescence rather than isolated compounds, the current studies aim to evaluate the preclinical safety of a full-spectrum composition (THC, CBD, minor cannabinoids, terpenes, and flavonoids) Cannabis sativa extract (CSE).

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1 week ago - This can be confusing because the Cannabis species also includes hemp. While cannabis seeds essentially contain no cannabinoids, cannabinoids are found in higher concentrations in cannabis flowers, leaves, and stalks.

Hemp flowers and herbage contain valuable phytocannabinoids, which are naturally occurring cannabinoids that are unique to the Cannabis plant [17]. All industrial hemp varieties contain THC, CBD, and other cannabinoids, although the concentrations in some varieties are very low to non-detectable.

Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available literature on the ecology, chemical composition, phytochemistry, pharmacology, traditional uses, industrial uses, and toxicology of Cannabis sativa. So far, 566 chemical compounds have been isolated from Cannabis, including 125 cannabinoids and 198 non-cannabinoids.

Indian hemp contains more than 60 cannabinoids including: cannabinol, cannabidiol, cannabinolic acid, cannabigerol, cannabicyclol, and various tetrahydrocannabinol isomers, the most important is delta-9-tetrahydrocannabinol (delta-9-THC).

Hemp seeds are the seeds of the Cannabis sativa plant. The seeds of the plant do not naturally contain THC or CBD.

May 7, 2024 - In addition to cannabinoids, the plant contains terpenoids such as β-myrcene, β-caryophyllene, D-limonene, linalool, piperidine, and P-cymene, as well as flavonoids such as quercetin. CBD is nonintoxicating as it does not demonstrate psychoactive activity. However, it exerts several beneficial ...

Hemp poisoning produces no clear-cut clinical signs.

6 days ago - Although chemotype I cannabis and ... uses. Hemp typically has lower concentrations of total THC and may have higher concentrations of cannabidiol (CBD), which potentially mitigates the psychoactive effects of THC...

May 30, 2023 - Cannabis sativa, also known as “hemp” or “weed,” is a versatile plant with various uses in medicine, agriculture, food, and cosmetics. This review attempts to evaluate the available literature on the ecology, chemical composition, phytochemistry, pharmacology, traditional uses, industrial uses, and toxicology of Cannabis sativa. So far, 566 chemical compounds have been isolated from Cannabis, including 125 cannabinoids and 198 non-cannabinoids.

January 17, 2024 - M.A. Costa, B.M. Fonseca, F. Marques, N.A. Teixeira, G. Correia-da-Silva. The psychoactive compound of Cannabis sativa, Δ9-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover. Toxicology. 6 August 2015.

December 4, 2018 - In the light of all these findings, in this review we explore the effects and the molecular mechanisms of CBD on inflammation and cancer processes, highlighting also the role of minor cannabinoids and noncannabinoids constituents of Δ9-THC deprived hemp. Cannabis sativa L.

The first biotype is used for narcotic purposes and is therefore defined as the “drug type”. The second biotype has an industrial use (or fiber-type), while the intermediate biotype is mainly used for medical purposes [209]. THC has a toxic effect and is used as a narcotic, whereas CBD is a cannabinoid mainly used in medicine without any major psychoactive effects. THC and CBD are the two major phytochemicals present in C. sativa, although at least 100 cannabinoid phenolic compounds typical of this plant have been found [210]. While in the early 20th century, hemp was widely cultivated for textile purposes [13], and Italy and Russia were the major European producers [103], later concerns about the effects of THC fostered the ban of all types of hemp without distinctions of uses for textile applications from narcotic use.

April 18, 2024 - Since then, Missouri has experienced an increase in cannabis · consumption poisonings and has identified reliable evidence of unique health and safety risks associated with · these products. At this time, the public should avoid products that contain Hemp-Derived Intoxicating · Cannabinoids until further notice.