NCBI
Benzodiazepine Pharmacology and Central Nervous System–Mediated Effects - PMC
Owing to the low therapeutic index of barbiturates, benzodiazepines (BZDs) became popular in this country and worldwide many decades ago for a wide range of conditions. Because of an increased understanding of pharmacology and physiology, the mechanisms ...
Benzodiazepine
class of psychoactive drugs
Factsheet
Factsheet
Benzodiazepines Drug class
Class identifiers
Wikipedia
Benzodiazepine - Wikipedia
2 weeks ago - By 1977, benzodiazepines were the ... prescription, but they remain frequently used worldwide. Benzodiazepines are depressants that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic ...
Cleveland Clinic
Benzodiazepines: What They Are, Uses, Side Effects & Risks
May 17, 2024 - Benzodiazepines tell your brain to release a neurotransmitter, gamma-aminobutyric acid (GABA). This neurotransmitter has a specific job: It makes your nervous system less active. The slowed activity can have the following effects: Amnestic: This word comes from a Greek word that means ...
What are the side effects of benzodiazepines?
What are the side effects of benzodiazepines?
Benzodiazepines, used for anxiety and insomnia, can cause drowsiness, dizziness, and coordination issues. Long-term use of benzodiazepine receptors may lead to dependence, withdrawal symptoms, panic disorder, and memory impairment. · They can also increase the risk of falls, respiratory distress, and paradoxical reactions. Combining with alcohol or other dangerous drugs intensifies risks. Consult a doctor for personalized medical advice.
recoveryteam.org
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
What are benzodiazepines, and how do they work?
What are benzodiazepines, and how do they work?
Benzodiazepines, prescription sedatives, and Class C drugs are central nervous system depressants with a potential for addiction. Common side effects of high doses include drowsiness and dizziness, paranoia, and other health problems. · Street benzos, obtained illegally, pose risks for young adults. The drugs, with varying half-lives, can lead to dependence and should be managed cautiously to avoid adverse reactions.
recoveryteam.org
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
Are benzodiazepines good or bad?
Are benzodiazepines good or bad?
Benzodiazepines can be effective in treating symptoms of anxiety and insomnia, but their long-term use is associated with dependence and withdrawal symptoms. Long-term use of benzodiazepines can lead to addiction and adverse effects, including respiratory depression. · While beneficial when prescribed and monitored carefully, caution is necessary due to potential risks. Consult healthcare professionals to weigh benefits against potential drawbacks and explore alternative treatments for certain conditions.
recoveryteam.org
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
NCBI
Benzodiazepines: Uses, Dangers, and Clinical Considerations - PMC
BZDs are a class of psychoactive drugs known for their depressant effect on the central nervous system (CNS). They quickly diffuse through the blood–brain barrier to affect the inhibitory neurotransmitter GABA and exert sedative effects. GABA is the most common neurotransmitter in the CNS, ...
Pharmacology Mentor
Benzodiazepines: A Complete Overview | Pharmacology Mentor
November 22, 2023 - Benzodiazepines (BZDs) are a class of psychoactive drugs that primarily act on the central nervous system (CNS). They modulate the neurotransmitter gamma-aminobutyric acid (GABA), enhancing its inhibitory effects. This results in various therapeutic actions, including sedation, muscle relaxation, ...
DEA
Benzodiazepines
Benzodiazepines are depressants that produce sedation and hypnosis, relieve anxiety and muscle spasms, and reduce seizures. The most common benzodiazepines are the prescription drugs Valium®, Xanax®, Halcion®, Ativan®, and Klonopin®. Shorter-acting benzodiazepines used to manage insomnia ...
Recovery Team
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
Benzodiazepines are a class of ... primary inhibitory neurotransmitter in the central nervous system, meaning it reduces the activity of nerve cells and helps regulate excessive neural firing....
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Benzoinfo
Mechanism of Action - Benzodiazepine Information Coalition
July 27, 2022 - Benzodiazepines work by enhancing a very important neurotransmitter called GABA (gamma-aminobutyric acid) at the GABA A receptor. This results in the sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties for which the drugs are prescribed.
ScienceDirect
Benzodiazepine - an overview | ScienceDirect Topics
Benzodiazepines exert sedative ... of internuncial neurons of the spinal cord. Benzodiazepines potentiate the actions of γ-aminobutyric acid (GABA), one of the two main inhibitory amino acid transmitters in the brain (glycine being the other)....
NCBI
Benzodiazepines I: Upping the Care on Downers: The Evidence of Risks, Benefits and Alternatives - PMC
Finally, both fast-acting/acute and delayed-action/chronic alternative treatments for anxiety and/or insomnia are discussed. Response to treatment—whether benzodiazepines, other pharmacological agents, or psychotherapy—should be determined based on functional recovery and not merely sedation.
WebMD
Anxiolytic Medications: Types and Side Effects
January 9, 2023 - There are different types of anxiolytic ... depressants. It’s not entirely clear how benzodiazepines work, but they raise levels of an amino acid in your brain called gamma-aminobutyric acid (GABA)....
MDPI
Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective
Benzodiazepines (BZDs) are a class of widely prescribed psychotropic drugs that target GABAA receptors (GABAARs) to tune inhibitory synaptic signaling throughout the central nervous system. Despite knowing their molecular target for over 40 years, we still do not fully understand the mechanism ...
Verywell Mind
Benzodiazepines Uses, Indications, and Side Effects
Benzodiazepines are medications often used to treat anxiety and insomnia. Read how they work, types, side effects, benefits, and risk of dependence.
ScienceDirect
Benzodiazepine Receptor - an overview | ScienceDirect Topics
In subject area: Pharmacology, Toxicology and Pharmaceutical Science · The GABAA/benzodiazepine receptor complex, which is also known as the central benzodiazepine receptor, is a heteromeric protein complex containing binding sites for classes of compounds such as GABA and benzodiazepines ...
Cleveland Clinic
Anxiolytics: What They Are, Uses, Side Effects & Types
May 1, 2024 - Anxiolytics are medications that treat anxiety and related conditions. Many drugs have this effect, and anxiolytics are among the most prescribed drugs worldwide.
ScienceDirect
Benzodiazepine Receptor Stimulating Agent - an overview | ScienceDirect Topics
In subject area: Pharmacology, Toxicology and Pharmaceutical Science · The BZRA hypnotics are allosteric modulators of gamma-aminobutyric acid (GABA) responses at the GABA-A receptor complex, which is a pentameric transmembrane structure with a central ion channel
CAMH
Anti-Anxiety Medications (Benzodiazepines) | CAMH
Overview of benzodiazepines, a group of medications that can help reduce anxiety and insomnia.
NCBI
Valium without dependence? Individual GABAA receptor subtype contribution toward benzodiazepine addiction, tolerance, and therapeutic effects - PMC
Benzodiazepines are one of the most prescribed medications as first-line treatment of anxiety, insomnia, and epilepsy around the world. Over the past two decades, advances in the neuropharmacological understanding of gamma aminobutyric acid (GABA)[A] ...