NCBI
Benzodiazepine Pharmacology and Central Nervous System–Mediated Effects - PMC
Owing to the low therapeutic index of barbiturates, benzodiazepines (BZDs) became popular in this country and worldwide many decades ago for a wide range of conditions. Because of an increased understanding of pharmacology and physiology, the mechanisms ...
Benzodiazepine
class of psychoactive drugs
Factsheet
Factsheet
Benzodiazepines Drug class
Class identifiers
Wikipedia
Benzodiazepine - Wikipedia
2 weeks ago - By 1977, benzodiazepines were the ... prescription, but they remain frequently used worldwide. Benzodiazepines are depressants that enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic ...
Cleveland Clinic
Benzodiazepines: What They Are, Uses, Side Effects & Risks
May 17, 2024 - Benzodiazepines tell your brain to release a neurotransmitter, gamma-aminobutyric acid (GABA). This neurotransmitter has a specific job: It makes your nervous system less active. The slowed activity can have the following effects: Amnestic: This word comes from a Greek word that means ...
What are the side effects of benzodiazepines?
What are the side effects of benzodiazepines?
Benzodiazepines, used for anxiety and insomnia, can cause drowsiness, dizziness, and coordination issues. Long-term use of benzodiazepine receptors may lead to dependence, withdrawal symptoms, panic disorder, and memory impairment. · They can also increase the risk of falls, respiratory distress, and paradoxical reactions. Combining with alcohol or other dangerous drugs intensifies risks. Consult a doctor for personalized medical advice.
recoveryteam.org
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
What are benzodiazepines, and how do they work?
What are benzodiazepines, and how do they work?
Benzodiazepines, prescription sedatives, and Class C drugs are central nervous system depressants with a potential for addiction. Common side effects of high doses include drowsiness and dizziness, paranoia, and other health problems. · Street benzos, obtained illegally, pose risks for young adults. The drugs, with varying half-lives, can lead to dependence and should be managed cautiously to avoid adverse reactions.
recoveryteam.org
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
Are benzodiazepines good or bad?
Are benzodiazepines good or bad?
Benzodiazepines can be effective in treating symptoms of anxiety and insomnia, but their long-term use is associated with dependence and withdrawal symptoms. Long-term use of benzodiazepines can lead to addiction and adverse effects, including respiratory depression. · While beneficial when prescribed and monitored carefully, caution is necessary due to potential risks. Consult healthcare professionals to weigh benefits against potential drawbacks and explore alternative treatments for certain conditions.
recoveryteam.org
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
NCBI
Benzodiazepines: Uses, Dangers, and Clinical Considerations - PMC
BZDs are a class of psychoactive drugs known for their depressant effect on the central nervous system (CNS). They quickly diffuse through the blood–brain barrier to affect the inhibitory neurotransmitter GABA and exert sedative effects. GABA is the most common neurotransmitter in the CNS, ...
Benzoinfo
Mechanism of Action - Benzodiazepine Information Coalition
July 27, 2022 - Benzodiazepines work by enhancing a very important neurotransmitter called GABA (gamma-aminobutyric acid) at the GABA A receptor. This results in the sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties for which the drugs are prescribed.
ScienceDirect
Benzodiazepine Receptor - an overview | ScienceDirect Topics
In subject area: Neuroscience · A Benzodiazepine Receptor is a specific type of receptor located on brain neurons that serves as the physiological target for the action of benzodiazepines, which are clinically and pharmacologically active compounds
Verywell Mind
Benzodiazepines Uses, Indications, and Side Effects
This reduces the excitability of nerve signals in your brain and slows it down. By slowing nerve signals in the brain, it leads to the relaxation of certain physiological and emotional responses. This results in a calming, tranquilizing feeling. Benzodiazepines have properties that make them ...
Recovery Team
Benzodiazepines: Mechanisms, Uses, and Concerns - Recovery Team
Benzodiazepines are a class of ... primary inhibitory neurotransmitter in the central nervous system, meaning it reduces the activity of nerve cells and helps regulate excessive neural firing....
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MDPI
Benzodiazepine Modulation of GABAA Receptors: A Mechanistic Perspective
Benzodiazepines (BZDs) are a class of widely prescribed psychotropic drugs that target GABAA receptors (GABAARs) to tune inhibitory synaptic signaling throughout the central nervous system. Despite knowing their molecular target for over 40 years, we still do not fully understand the mechanism ...
DEA
Benzodiazepines
Benzodiazepines are depressants that produce sedation and hypnosis, relieve anxiety and muscle spasms, and reduce seizures. The most common benzodiazepines are the prescription drugs Valium®, Xanax®, Halcion®, Ativan®, and Klonopin®. Shorter-acting benzodiazepines used to manage insomnia ...
ScienceDirect
Benzodiazepine - an overview | ScienceDirect Topics
GABA is the most common neurotransmitter in the central nervous system and can be found in high concentration in both the cortex as the limbic system. It has an inhibitory effect and reduces the excitability of the neurons, resulting in a calming effect on the brain.
NCBI
Benzodiazepines - StatPearls - NCBI Bookshelf
Activation of benzodiazepine receptors causes a conformational change to a central pore, allowing chloride ions to enter the neuron. The influx of the chloride anion results in hyperpolarization of the neuron, resulting in CNS depression.[15] Benzodiazepines increase the frequency of the GABA-A ...
Medicalnewstoday
Benzodiazepines: Uses, types, side effects, and risks
January 5, 2024 - Doctors prescribe benzodiazepines for anxiety, insomnia, and other purposes. However, there is a risk of dependence and interactions with other drugs. Learn more here.
NCBI
Benzodiazepines I: Upping the Care on Downers: The Evidence of Risks, Benefits and Alternatives - PMC
Benzodiazepines are some of the most commonly prescribed medications in the world. These sedative-hypnotics can provide rapid relief for symptoms like anxiety and insomnia, but are also linked to a variety of adverse effects (whether used long-term, short-term, ...
Pharmacology Mentor
Benzodiazepines: A Complete Overview | Pharmacology Mentor
November 22, 2023 - Benzodiazepines (BZDs) are a class of psychoactive drugs that primarily act on the central nervous system (CNS). They modulate the neurotransmitter gamma...
Nature
Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect | Molecular Psychiatry
Benzodiazepines (BZDs) have been a standard treatment for anxiety disorders for decades, but the neuronal circuit interactions mediating their anxiolytic effect remain largely unknown. Here, we find that systemic BZDs modulate central amygdala (CEA) microcircuit activity to gate amygdala output.
CAMH
Anti-Anxiety Medications (Benzodiazepines) | CAMH
Overview of benzodiazepines, a group of medications that can help reduce anxiety and insomnia.
Drugs
Benzodiazepines: Uses, Side Effects, Interactions & Warnings
May 22, 2024 - Learn about the benzodiazepine drug class including their uses, a list of common benzodiazepines, side effects, warnings and withdrawal symptoms.